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Abstract The fragile-X[fra X ] or Martin-Bell syndrome is the mentally common familial cause of mental retardation and is characterized by the presence of an Xq Figures Figure 1 Representative Southern site analysis with…. The fragile-X[fra X ] or Martin-Bell syndrome is the most common familial cause of mental retardation and free social sites to meet people characterized by the presence of an Xq In dating to identify forum sex north charleston cytogenetically normal yet mentally retarded males without a known cause of their retardation had expansion of the CGG repeat segment of the FMR-I gene, molecular genetic studies using Southern hybridization were performed with two DNA probes fxa and Ox1.

DNA studies were performed on 20 None of the 20 males showed expansion of the CGG repeat of the FMR-1 gene retarded with the two probes used in this study. See all similar articles. Create file Cancel. Gov't Actions. Search: Search. The fragile X syndrome. Choose a collection: Unable to load your collection due to an error Please try again.

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MeSH terms Adolescent Actions. Save Cancel. While heterogeneous single base pair substitutions, or small deletions or insertions in the FMR-I gene could exist in our patients, aberrations in other X-linked mental retardation genes, not identified to date best app for hooking up women whose gene product can produce a phenotype similar to fra Xeither independently or in conjunction with the recently identified FMR-I protein, should be considered and are under investigation.

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Our study supports the idea that major FMR-I gene expansion free internet dating sites uk with Southern hybridization is rare in cytogenetically normal mentally retarded males, including those with physical and behavioural features seen in the fra X syndrome.

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Molecular genetic analysis of mentally retarded males with features of the fragile-x syndrome

Mental status and fragile X expression in relation to FMR-1 gene mutation. Figure 1 Representative Southern blot analysis with Ox1. Arrows correspond to expansion of the CGG repeat in an affected fra X syndrome male top and 2. Unable to load your delegates due to an error Please try again. Related dating site for middle schoolers MedGen.

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